Adenosine-2'-monophosphate, CAS 130-49-4

Product Description: Adenosine-2'-monophosphate (2'-AMP) is converted by extracellular 2’,3'-CAMP. Adenosine-2'-monophosphate is further metabolized to extracellular adenosine (a mechanism called the extracellular 2’,3’-cAMP-adenosine pathway). Adenosine-2'-monophosphate inhibits LPS-induced TNF-α and CXCL10 production via A2A receptor activation[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C10H14N5O7P

References: [1]Jackson EK, Gillespie DG, Dubey RK. 2'-AMP and 3'-AMP inhibit proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors. J Pharmacol Exp Ther. 2011;337(2):444‐450./[2]Newell EA, Exo JL, Verrier JD, et al. 2',3'-cAMP, 3'-AMP, 2'-AMP and adenosine inhibit TNF-α and CXCL10 production from activated primary murine microglia via A2A receptors. Brain Res. 2015;1594:27‐35.

CAS Number: 130-49-4

Molecular Weight: 347.22

Compound Purity: 98.0

Research Area: Neurological Disease

Solubility: DMSO : 62.5 mg/mL (ultrasonic;warming;heat to 80°C)/H2O : 50 mg/mL (ultrasonic;adjust pH to 7 with NaOH)

Target: Adenosine Receptor;Endogenous Metabolite

• Artikelnummer: MEXHY-124151-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-124151-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK