Aprotinin, CAS 9087-70-1

Product Description: Aprotinin is a bovine pancreatic trypsin inhibitor (BPTI) inhibitor which inhibits trypsin and chymotrypsin with Kis of 0.06 pM and 9 nM, respectively.

Applications: COVID-19-anti-virus

Formula: C284H432N84O79S7

References: [1]Fritz H, et al. Biochemistry and applications of aprotinin, the kallikrein inhibitor from bovine organs. Arzneimittelforschung. 1983;33(4):479-94./[2]Levy JH, et al. Efficacy and safety of aprotinin in cardiac surgery. Orthopedics. 2004 Jun;27(6 Suppl):s659-62./[3]Venturini G, et al. Aprotinin, the first competitive protein inhibitor of NOS activity.Biochem Biophys Res Commun. 1998 Aug 10;249(1):263-5/[4]Sperzel M, et al. Evaluation of aprotinin and tranexamic acid in different in vitro and in vivo models of fibrinolysis, coagulation and thrombus formation. J Thromb Haemost. 2007 Oct;5(10):2113-8. Epub 2007 Jul 31./[5]Davis R, et al. Aprotinin. A review of its pharmacology and therapeutic efficacy in reducing blood loss associated withcardiac surgery. Drugs. 1995 Jun;49(6):954-83./[6]Sabbagh MJ, et al. Aprotinin exacerbates left ventricular dysfunction after ischemia/reperfusion in mice lacking tumor necrosis factor receptor I. J Cardiovasc Pharmacol. 2008 Oct;52(4):355-62./[7]Levy JH, et al. Efficacy and safety of aprotinin in cardiac surgery. Orthopedics. 2004 Jun;27(6 Suppl):s659-62.

CAS Number: 9087-70-1

Molecular Weight: 6511.44

Compound Purity: 99.29

Research Area: Cardiovascular Disease; Cancer

Solubility: DMSO : 66.67 mg/mL (ultrasonic;adjust pH to 3 with HCl)/H2O : 100 mg/mL (ultrasonic)

Target: Influenza Virus;Ser/Thr Protease

• Artikelnummer: MEXHY-P0017-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P0017-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK