Artobiloxanthone

Product Description: Artobiloxanthone (Compound AA3) exhibits antitumor activity, particularly against oral squamous cell carcinoma (OSCC). Artobiloxanthone inhibits Akt/mTOR pathway and STAT3 pathway, inhibits proliferation of SAS and T.Tn (with IC50 of 11 and 22 μM), and inhibits the cancer cell migration. Artobiloxanthone arrests cell cycle at S phase, and induces apoptosis in OSCC cells through activation of caspase 3/9[1].

Applications: Cancer-Kinase/protease

Formula: C25H22O7

References: [1]Aswathy M, et al., Natural Prenylflavones from the Stem Bark of Artocarpus altilis: Promising Anticancer Agents for Oral Squamous Cell Carcinoma Targeting the Akt/mTOR/STAT-3 Signaling Pathway. ACS Omega. 2024 May 24;9(23):24252-24267.

Molecular Weight: 434.44

Research Area: Cancer

Target: Apoptosis;Bcl-2 Family;Caspase;COX;MMP;STAT

• Artikelnummer: MEXHY-N12960-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N12960-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK