β-Nicotinamide mononucleotide, CAS 1094-61-7

Product Description: β-nicotinamide mononucleotide (β-NM) is a product of the nicotinamide phosphoribosyltransferase (NAMPT) reaction and a key NAD+ intermediate. The pharmacological activities of β-nicotinamide mononucleotide include its role in cellular biochemical functions, cardioprotection, diabetes, Alzheimer's disease, and complications associated with obesity[1].

Formula: C11H15N2O8P

References: [1]Poddar SK, et al. Nicotinamide Mononucleotide: Exploration of Diverse Therapeutic Applications of a Potential Molecule. Biomolecules. 2019;9(1):34. Published 2019 Jan 21./[2]Lv H, et al. NAD+ Metabolism Maintains Inducible PD-L1 Expression to Drive Tumor Immune Evasion [published online ahead of print, 2020 Nov 3]. Cell Metab. 2020;S1550-4131(20)30554-4./[3]Li J, et al. p53 prevents doxorubicin cardiotoxicity independently of its prototypical tumor suppressor activities. Proc Natl Acad Sci U S A. 2019;116(39):19626-19634./[4]Yoshino J, et al Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metab. 2011;14(4):528-536.

CAS Number: 1094-61-7

Molecular Weight: 334.22

Compound Purity: 99.90

Research Area: Cancer; Neurological Disease

Solubility: H2O : 83.33 mg/mL (ultrasonic)

Target: Endogenous Metabolite

• Artikelnummer: MEXHY-F0004-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-F0004-100
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK