Berberine (hemisulfate), CAS 316-41-6

Product Description: Berberine hemisulfate is the hemisulfate form of Berberine (HY-N0716). Berberine hemisulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian. Berberine hemisulfate exhibits anti-inflammatory, antibiobic, antitumor, cardiovascular protective and neuroprotective activity[1][2][3][4][5][6].

Formula: C20H18NO4.1/2O4S

References: [1]Cai Y, et al. Berberine inhibits the growth of human colorectal adenocarcinoma in vitro and in vivo. J Nat Med. 2014 Jan;68(1):53-62./[2]Cui HX, et al. Preparation and Evaluation of Antidiabetic Agents of Berberine Organic Acid Salts for Enhancing the Bioavailability. Molecules. 2018 Dec 28;24(1):103./[3]Boberek JM, et al., Genetic evidence for inhibition of bacterial division protein FtsZ by berberine. PLoS One. 2010 Oct 29;5(10):e13745. /[4]Remppis A, et al., Rhizoma Coptidis inhibits LPS-induced MCP-1/CCL2 production in murine macrophages via an AP-1 and NFkappaB-dependent pathway. Mediators Inflamm. 2010;2010:194896./[5]Bae J, et al., Berberine protects 6-hydroxydopamine-induced human dopaminergic neuronal cell death through the induction of heme oxygenase-1. Mol Cells. 2013 Feb;35(2):151-7. /[6]Ye Y, et al., Efficacy and Safety of Berberine Alone for Several Metabolic Disorders: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Front Pharmacol. 2021 Apr 26;12:653887.

CAS Number: 316-41-6

Molecular Weight: 384.40

Compound Purity: 98.95

Research Area: Cancer; Infection; Metabolic Disease; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease

Solubility: 10 mM in DMSO

Target: Akt;Antibiotic;AP-1;Apoptosis;Autophagy;Bacterial;Caspase;JNK;NF-κB;PI3K;Reactive Oxygen Species;Topoisomerase

• Artikelnummer: MEXHY-N0716A-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N0716A-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK