Product Description: Caulophyllogenin is a triterpene saponin extracted from M. polimorpha. Caulophyllogenin is a partial PPARγ agonist, with an EC50 of 12.6 μM. Caulophyllogenin can be used for the research of type-2 diabetes, obesity, metabolic syndrome and inflammation[1][2].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C30H48O5
References: [1]Montanari R, et, al. Screening of saponins and sapogenins from Medicago species as potential PPARγ agonists and X-ray structure of the complex PPARγ/caulophyllogenin. Sci Rep. 2016 Jun 10; 6:27658./[2]Zhang Y, et, al. Studies on cytotoxic triterpene saponins from the leaves of Aralia elata. Food Chem. 2013 May 1;138(1):208-13.
CAS Number: 52936-64-8
Molecular Weight: 488.70
Research Area: Metabolic Disease; Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: PPAR