Cimicifugoside, CAS 66176-93-0

Product Description: Cimicifugoside, a triterpenoid isolated from Cimicifuga simplex, is a novel specific nucleoside transport inhibitor that displays synergistic potentiation of methotrexate cytotoxicity[1]. Cimicifugoside shows immunosuppressive activity, which is preferentially directed toward B-cell function with larger doses being required for suppression of T-cell function[2].

Applications: COVID-19-immunoregulation

Formula: C37H54O11

References: [1]Yawata A, et al. Inhibition of nucleoside transport and synergistic potentiation of methotrexate cytotoxicity by cimicifugoside, a triterpenoid from Cimicifuga simplex. Eur J Pharm Sci. 2009 Nov 5;38(4):355-61./[2]Hemmi H, et al. The immune response of splenic lymphocytes after cimicifugoside treatment in vitro and pretreatment in vivo. J Pharmacobiodyn. 1980 Dec;3(12):643-8.

CAS Number: 66176-93-0

Molecular Weight: 674.82

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Others

• Artikelnummer: MEXHY-N7119-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N7119-1
• Green Labware: Nein
• Verpackungseinheit: 1mg
• Mengeneinheit: STK