Crocetin monomethyl ester, CAS 25368-09-6

Product Description: Crocetin monomethyl ester, isolated from Crocus sativus, possesses anti-inflammatory, neuroprotective and antioxidant activity[1][2]. Crocetin monomethyl ester promotes clearance of amyloid-β by inducing autophagy via the STK11/LKB1-mediated AMPK pathway[4].

Applications: COVID-19-immunoregulation

Formula: C21H26O4

References: [1]Tseng TH, et al. Crocetin protects against oxidative damage in rat primary hepatocytes. Cancer Lett. 1995 Oct 20;97(1):61-7./[2]Ahmad AS, et al. Neuroprotection by crocetin in a hemi-parkinsonian rat model. Pharmacol Biochem Behav. 2005 Aug;81(4):805-13./[3]Nam KN, et al. Anti-inflammatory effects of crocin and crocetin in rat brain microglial cells. Eur J Pharmacol. 2010 Dec 1;648(1-3):110-6./[4]Wani A, Al Rihani SB, Sharma A, et al. Crocetin promotes clearance of amyloid-β by inducing autophagy via the STK11/LKB1-mediated AMPK pathway. Autophagy. 2021;17(11):3813-3832.

CAS Number: 25368-09-6

Molecular Weight: 342.43

Compound Purity: 98.44

Research Area: Inflammation/Immunology; Neurological Disease

Solubility: DMSO : 31.25 mg/mL (ultrasonic)

Target: Amyloid-β

• Artikelnummer: MEXHY-N6904-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N6904-10.1
• Green Labware: Nein
• Verpackungseinheit: 10mM/1mL
• Mengeneinheit: STK