Product Description: Cyclocurcumin is a potent p38α inhibitor. Cyclocurcumin shows antirheumatic, antivasoconstrictive and antioxidant activities[1][2][3].
Applications: COVID-19-immunoregulation
Formula: C21H20O6
References: [1]Fu M, et al. Cyclocurcumin, a curcumin derivative, exhibits immune-modulating ability and is a potential compound for the treatment of rheumatoid arthritis as predicted by the MM-PBSA method. Int J Mol Med. 2017 May;39(5):1164-1172./[2]Kim K, et al. Cyclocurcumin, an Antivasoconstrictive Constituent of Curcuma longa (Turmeric). J Nat Prod. 2017 Jan 27;80(1):196-200./[3]Li Y, et al. Antioxidant properties and free radical scavenging mechanisms of cyclocurcumin. New Journal of Chemistry, 2018, 42(15): 12698-12705.
CAS Number: 153127-42-5
Molecular Weight: 368.38
Compound Purity: 99.48
Research Area: Inflammation/Immunology; Cardiovascular Disease
Solubility: 10 mM in DMSO
Target: p38 MAPK