ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid, CAS 57719-81-0

Product Description: ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid is an anti-melanin synthesis tyrosinase inhibitor, which can be isolated from Pteris fern. ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid regulates the melanogenesis transcription factor microphthalmia-associated transcription factor (MITF). The 11α-OH, 15-oxo and 16-en moieties of ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid are key fragments that inhibit melanin synthesis. The 19-COOH moiety has been implicated in the inhibition of cytotoxicity associated with 11α-OH KA and related compounds[1].

Applications: Metabolism-sugar/lipid metabolism

Formula: C20H28O4

References: [1]Kuroi A, et al. The Importance of 11伪-OH, 15-oxo, and 16-en Moieties of 11伪-Hydroxy-15-oxo-kaur-16-en-19-oic Acid in Its Inhibitory Activity on Melanogenesis. Skin Pharmacol Physiol. 2017;30(4):205-215.

CAS Number: 57719-81-0

Molecular Weight: 332.43

Research Area: Others

Solubility: 10 mM in DMSO

Target: Tyrosinase

• Artikelnummer: MEXHY-N3810-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N3810-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK