Episilvestrol, CAS 697235-39-5

Product Description: Episilvestrol is a derivative of silvestrol, isolated from the fruits and twigs of Aglaia perviridis, and is a specific eIF4A-targeting translation inhibitor, with antitumor activity.

Applications: Cancer-programmed cell death

Formula: C34H38O13

References: [1]Chambers JM, et al. Synthesis of biotinylated episilvestrol: highly selective targeting of the translation factors eIF4AI/II. Org Lett. 2013 Mar 15;15(6):1406-9./[2]Hwang BY, et al. Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris. J Org Chem. 2004 May 14;69(10):3350-8./[3]Daker M, et al. Inhibition of nasopharyngeal carcinoma cell proliferation and synergism of cisplatin with silvestrol and episilvestrol isolated from Aglaia stellatopilosa. Exp Ther Med. 2016 Jun;11(6):2117-2126. Epub 2016 Mar 29.

CAS Number: 697235-39-5

Molecular Weight: 654.66

Compound Purity: 99.86

Research Area: Cancer

Solubility: DMSO : 25 mg/mL (ultrasonic)

Target: Autophagy;Eukaryotic Initiation Factor (eIF)

• Artikelnummer: MEXHY-15359-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-15359-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK