Euphol, CAS 514-47-6

Product Description: Euphol is a tetracyclic triterpene alcohol isolated from the sap of Euphorbia tirucalli with anti-mutagenic, anti-inflammatory and immunomodulatory effects, orally active. Euphol inhibits the monoacylglycerol lipase (MGL) activity via a reversible mechanism (IC50=315 nM). MGL inhibition in the periphery modulates the endocannabinoid system to block the development of inflammatory pain[1].

Applications: COVID-19-immunoregulation

Formula: C30H50O

References: [1]Dutra RC, et al. Euphol, a tetracyclic triterpene produces antinociceptive effects in inflammatory and neuropathic pain: the involvement of cannabinoid system. Neuropharmacology. 2012 Sep;63(4):593-605./[2]Wang L, et al. Euphol arrests breast cancer cells at the G1 phase through the modulation of cyclin D1, p21 and p27 expression. Mol Med Rep. 2013 Oct;8(4):1279-85./[3]Wang L, et al. Euphol arrests breast cancer cells at the G1 phase through the modulation of cyclin D1, p21 and p27 expression. Mol Med Rep. 2013 Oct;8(4):1279-85.

CAS Number: 514-47-6

Molecular Weight: 426.72

Compound Purity: 99.01

Research Area: Inflammation/Immunology

Solubility: DMSO : 25 mg/mL (ultrasonic)

Target: Endogenous Metabolite;MAGL

• Artikelnummer: MEXHY-N0313-50
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N0313-50
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK