Fustin, CAS 20725-03-5

Product Description: Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) is a potent amyloid β (Aβ) inhibitor. Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) increases the expression of acetylcholine (ACh) levels, choline acetyltransferase (ChAT) activity, and ChAT gene induced by Aβ (1-42). Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) decreases in acetyl cholinesterase (AChE) activity and AChE gene expression induced by Aβ (1-42). Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) increases muscarinic M1 receptor gene expression and muscarinic M1 receptor binding activity. Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) can be used for Alzheimer's disease research[1].

Applications: Neuroscience-Neurodegeneration

Formula: C15H12O6

References: [1]Jin CH, et, al. Fustin flavonoid attenuates beta-amyloid (1-42)-induced learning impairment. J Neurosci Res. 2009 Dec;87(16):3658-70.

CAS Number: 20725-03-5

Molecular Weight: 288.25

Compound Purity: 98.0

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Amyloid-β;Cholinesterase (ChE);mAChR

• Artikelnummer: MEXHY-N8376-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N8376-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK