Gallinamide A (TFA), CAS 1352920-57-0

Product Description: Gallinamide A TFA is a linearly depositing peptide and a potent inhibitor of cathepsin L (CatL) (IC50: 17.6 pM). Gallinamide A TFA inhibits SARS-CoV-2 infection by inhibiting CatL (EC50: 28 nM). Gallinamide A TFA also inhibits Plasmodium falciparum (IC50: 50 nM)[1][2].

Formula: C33H53F3N4O9

References: [2]Stoye A, et al. Falcipain Inhibitors Based on the Natural Product Gallinamide A Are Potent in Vitro and in Vivo Antimalarials. J Med Chem. 2019 Jun 13;62(11):5562-5578./[1]Ashhurst AS, et al. Potent in vitro anti-SARS-CoV-2 activity by gallinamide A and analogues via inhibition of cathepsin L. bioRxiv [Preprint]. 2020 Dec 24:2020.12.23.424111.

CAS Number: 1352920-57-0

Molecular Weight: 706.79

Compound Purity: 99.85

Research Area: Infection

Solubility: 10 mM in DMSO

Target: Cathepsin;Parasite;SARS-CoV

• Artikelnummer: MEXHY-N10109A-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N10109A-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK