Ganodermanondiol, CAS 107900-76-5

Product Description: Ganodermanondiol is a melanogenesis inhibitor isolated from the Ganoderma lucidum[1].Ganodermanondiol exhibits potent cytoprotective effects on tert-butyl hydroperoxide-induced hepatotoxicity[2]. Ganodermanondiol shows significant anti-HIV-1 protease activity with an IC50 of 90 μM[3]. Ganodermanondiol exhibits a strong anticomplement activity against the classical pathway of the complement system with an IC50 of 41.7μM[4].

Applications: COVID-19-anti-virus

Formula: C30H48O3

References: [1]Kim JW, et al. Effects of Ganodermanondiol, a New Melanogenesis Inhibitor from the Medicinal Mushroom Ganoderma lucidum. Int J Mol Sci. 2016 Oct 27;17(11)./[2]Li B, et al. Protective effect of ganodermanondiol isolated from the Lingzhi mushroom against tert-butyl hydroperoxide-induced hepatotoxicity through Nrf2-mediated antioxidant enzymes. Food Chem Toxicol. 2013 Mar;53:317-24./[3]Min BS, et al. Triterpenes from the spores of Ganoderma lucidum and their inhibitory activity against HIV-1 protease. Chem Pharm Bull (Tokyo). 1998 Oct;46(10):1607-12./[4]Min BS, et al. Anticomplement activity of terpenoids from the spores of Ganoderma lucidum. Planta Med. 2001 Dec;67(9):811-4.

CAS Number: 107900-76-5

Molecular Weight: 456.70

Research Area: Infection

Solubility: 10 mM in DMSO

Target: HIV Protease

• Artikelnummer: MEXHY-N2996-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N2996-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK