Gardenin A, CAS 21187-73-5

Product Description: Gardenin A is an orally active and synthetic PMF analogue with the neurotrophic effect for neurite outgrowth and neuronal differentiation. Gardenin A promotes neuritogenesis via activating MAPK/ERK, PKC, and PKA, but not TrkA, CREB signaling pathways. Gardenin A also has sedative, anxiolytic, antidepressant, and anticonvulsant effects[1][2].

Applications: COVID-19-anti-virus

Formula: C21H22O9

References: [1]Chiu SP, et al. Neurotrophic action of 5-hydroxylated polymethoxyflavones: 5-demethylnobiletin and gardenin A stimulate neuritogenesis in PC12 cells. J Agric Food Chem. 2013 Oct 2;61(39):9453-63. /[2]Alonso-Castro AJ, et al. Evaluation of the neuropharmacological effects of Gardenin A in mice. Drug Dev Res. 2020 Aug;81(5):600-608.

CAS Number: 21187-73-5

Molecular Weight: 418.39

Research Area: Inflammation/Immunology; Neurological Disease

Solubility: 10 mM in DMSO

Target: ERK;PAK

• Artikelnummer: MEXHY-N8303-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N8303-1
• Green Labware: Nein
• Verpackungseinheit: 1mg
• Mengeneinheit: STK