Guttiferone G, CAS 666174-75-0

Product Description: Guttiferone G inhibits recombinant human SIRT1 and SIRT2 (IC50: 9 and 22 μM, respectively). Guttiferone G is weakly cytotoxic in A2780 human ovarian cell line (IC50: 8.0 μg/mL). Guttiferone G can be isolated from Garcinia macrophylla[1][2].

Applications: Cancer-programmed cell death

Formula: C43H58O6

References: [1]Williams RB, et al. A novel cytotoxic guttiferone analogue from Garcinia macrophylla from the Suriname rainforest. Planta Med. 2003 Sep;69(9):864-6./[2]Gey C, et al. Phloroglucinol derivatives guttiferone G, aristoforin, and hyperforin: inhibitors of human sirtuins SIRT1 and SIRT2. Angew Chem Int Ed Engl. 2007;46(27):5219-22.

CAS Number: 666174-75-0

Molecular Weight: 670.92

Research Area: Others

Solubility: 10 mM in DMSO

Target: Sirtuin

• Artikelnummer: MEXHY-N9892-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N9892-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK