Hamamelitannin, CAS 469-32-9

Product Description: Hamamelitannin, a polyphenol extracted from the bark of Hamamelis virginiana, is a quorum-sensing (QS) inhibitor. Hamamelitannin increases antibiotic susceptibility of staphylococcus aureus biofilms by affecting peptidoglycan biosynthesis and eDNA release[1][2].

Applications: COVID-19-immunoregulation

Formula: C20H20O14

References: [1]Kiran MD, et al. Discovery of a quorum-sensing inhibitor of drug-resistant staphylococcal infections by structure-based virtual screening. Mol Pharmacol. 2008 May;73(5):1578-86./[2]Cobrado L, et al. In vivo antibiofilm effect of cerium, chitosan and hamamelitannin against usual agents of catheter-related bloodstream infections. J Antimicrob Chemother. 2013 Jan;68(1):126-30./[3]Sánchez-Tena S, et al. Hamamelitannin displays specific cytotoxic activity against colon cancer cells. J Nat Prod. 2012 Jan 27;75(1):26-33.

CAS Number: 469-32-9

Molecular Weight: 484.36

Research Area: Infection

Solubility: 10 mM in DMSO

Target: Bacterial

• Artikelnummer: MEXHY-N4117-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N4117-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK