Irigenin, CAS 548-76-5

Product Description: Irigenin is a is a lead compound, and mediates its anti-metastatic effect by specifically and selectively blocking α9β1 and α4β1 integrins binding sites on C-C loop of Extra Domain A (EDA). Irigenin shows anti-cancer properties. It sensitizes TRAIL-induced apoptosis via enhancing pro-apoptotic molecules in gastric cancer cells[1].

Applications: Cancer-programmed cell death

Formula: C18H16O8

References: [1]Amin A, et al. Irigenin, a novel lead from Western Himalayan chemiome inhibits Fibronectin-Extra Domain A induced metastasis in Lung cancer cells. Sci Rep. 2016 Nov 16;6:37151./[2]Xu Y, et al. Irigenin sensitizes TRAIL-induced apoptosis via enhancing pro-apoptotic molecules in gastric cancer cells. Biochem Biophys Res Commun. 2018 Feb 12;496(3):998-1005.

CAS Number: 548-76-5

Molecular Weight: 360.31

Compound Purity: 99.84

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Apoptosis;Integrin

• Artikelnummer: MEXHY-N2587-50
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N2587-50
• Green Labware: Nein
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK