Isojacareubin, CAS 50597-93-8

Product Description: Isojacareubin can be isolated from Hypericum japonicum. Isojacareubin covalently inhibits SARS-CoV-2 3CLpro. Isojacareubin also has anti-helicobacter activity. Isojacareubin inhibits PKC, and suppresses hepatocellular carcinoma metastasis and induces apoptosis[1][2][3].

Formula: C18H14O6

References: [1]Kyoko Ishiguro, et al. An isopentenylated flavonol from Hypericum japonicum. Phytochemistry. 1993. 32 (6), 1583-1585./[2]Yuan X, et al. Inhibition of protein kinase C by isojacareubin suppresses hepatocellular carcinoma metastasis and induces apoptosis in vitro and in vivo. Sci Rep. 2015 Aug 6;5:12889./[3]Khan A, et al. Discovery of Isojacareubin as a covalent inhibitor of SARS-CoV-2 main protease using structural and experimental approaches. J Med Virol. 2023 Feb;95(2):e28542.

CAS Number: 50597-93-8

Molecular Weight: 326.30

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Apoptosis;Bacterial;PKC;SARS-CoV

• Artikelnummer: MEXHY-N8306-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N8306-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK