Jasplakinolide, CAS 102396-24-7

Product Description: Jasplakinolide is a potent actin polymerization inducer and stabilizes pre-existing actin filaments. Jasplakinolide binds to F-actin competitively with phalloidin with a Kd of 15 nM. Jasplakinolide, a naturally occurring cyclic peptide from the marine sponge, has both fungicidal and anti-cancer activity[1][2].

Applications: COVID-19-immunoregulation

Formula: C36H45BrN4O6

References: [1]Holzinger A, et al. Jasplakinolide: an actin-specific reagent that promotes actin polymerization. Methods Mol Biol. 2009;586:71-87./[2]Bubb MR, et al. Jasplakinolide, a cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin. J Biol Chem. 1994 May 27;269(21):14869-71.

CAS Number: 102396-24-7

Molecular Weight: 709.67

Compound Purity: 99.0

Research Area: Cancer; Infection

Solubility: DMSO : 10 mg/mL (ultrasonic;warming)

Target: Arp2/3 Complex;Fungal

• Artikelnummer: MEXHY-P0027-50UG
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P0027-50UG
• Green Labware: Nein
• Verpackungseinheit: 50 μg
• Mengeneinheit: STK