Juglone, CAS 481-39-0

Product Description: Juglone (5-hydroxy-1,4-naphthalenedione) is a yellow dye that can be extracted from Juglans regia. Juglone induces apoptosis through the mitochondrial pathway. Juglone has antibacterial and antitumor activity[1][2][3].

Applications: COVID-19-immunoregulation

Formula: C10H6O3

References: [1]Zmantar T, et al. Use of juglone as antibacterial and potential efflux pump inhibitors in Staphylococcus aureus isolated from the oral cavity. Microb Pathog. 2016 Dec;101:44-49./[2]Ji YB, et al. Juglone-induced apoptosis in human gastric cancer SGC-7901 cells via the mitochondrial pathway. Exp Toxicol Pathol. 2011 Jan;63(1-2):69-78./[3]Peng X, et al. Juglone prevents metabolic endotoxemia-induced hepatitis and neuroinflammation via suppressing TLR4/NF-κB signaling pathway in high-fat diet rats. Biochem Biophys Res Commun. 2015 Jul 3;462(3):245-50.

CAS Number: 481-39-0

Molecular Weight: 174.16

Compound Purity: 99.88

Research Area: Cancer; Infection; Inflammation/Immunology

Solubility: DMSO : 50 mg/mL (ultrasonic)/Ethanol : 10 mg/mL (ultrasonic)

Target: Apoptosis;Bacterial;NF-κB;Toll-like Receptor (TLR)

• Artikelnummer: MEXHY-N6949-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N6949-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK