Kauran-16,17-diol, CAS 16836-31-0

Product Description: Kauran-16,17-diol (ent-Kauran-16β,17-diol), a natural diterpene, posseses anti-tumor and inducing-apoptosis activity, with a IC50 of 17 μM on inhibiting NO production in LPS-stimulated RAW 264.7 macrophages[1][2].

Applications: COVID-19-immunoregulation

Formula: C20H34O2

References: [1]Alvaro Morales, et al. The natural diterpene ent-16β-17α-dihydroxykaurane down-regulates Bcl-2 by disruption of the Ap-2α/Rb transcription activating complex and induces E2F1 up-regulation in MCF-7 cells. Apoptosis. 2011 Dec;16(12):1245-52./[2]Nguyen Xuan Nhiem, et al. New ent-kauranes from the fruits of Annona glabra and their inhibitory nitric oxide production in LPS-stimulated RAW264.7 macrophages. Bioorg Med Chem Lett. 2015 Jan 15;25(2):254-8.

CAS Number: 16836-31-0

Molecular Weight: 306.48

Compound Purity: 99.51

Research Area: Cancer; Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Apoptosis

• Artikelnummer: MEXHY-N7422-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N7422-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK