Product Description: Kushenol B is an isoprenoid flavonoid isolated from S. flavescens, has antimicrobial, anti-inflammatory and antioxidant activities[1]. Kushenol B has inhibitory activity against cAMP phosphodiesterase (PDE), with an IC50 of 31 µM[1].
Applications: COVID-19-immunoregulation
Formula: C30H36O6
References: [1]Han-Tian Fan, et al. The rational search for PDE10A inhibitors from Sophora flavescens roots using pharmacophore‑ and docking‑based virtual screening. Mol Med Rep
CAS Number: 99217-64-8
Molecular Weight: 492.60
Research Area: Infection; Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: Phosphodiesterase (PDE)