Lactimidomycin, CAS 134869-15-1

Product Description: Lactimidomycin is a glutarimide-containing compound isolated from Streptomyces. Lactimidomycin is a potent inhibitor of eukaryotic translation elongation. Lactimidomycin has a potent antiproliferative effect on tumor cell lines and selectively inhibit protein translation. Lactimidomycin inhibits protein synthesis with an IC50 value of 37.82 nM. Lactimidomycin is also a potent and non-toxic inhibitor of dengue virus 2 and other RNA viruses. Anticancer and antiviral activities[1][2].

Applications: COVID-19-anti-virus

Formula: C26H35NO6

References: [1]Schneider-Poetsch T, et al. Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin. Nat Chem Biol. 2010 Mar;6(3):209-217./[2]Carocci M, et al. Lactimidomycin is a broad-spectrum inhibitor of dengue and other RNA viruses. Antiviral Res. 2016 Apr;128:57-62.

CAS Number: 134869-15-1

Molecular Weight: 457.56

Compound Purity: 99.0

Research Area: Cancer; Infection

Solubility: DMSO : 5.72 mg/mL (ultrasonic;warming)

Target: Dengue virus;Flavivirus

• Artikelnummer: MEXHY-18979-200UG
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-18979-200UG
• Green Labware: Nein
• Verpackungseinheit: 200 μg
• Mengeneinheit: STK