Product Description: Leucomycin A13 is a macrolide antibiotic and a component of the leucomycin complex originally isolated from S. kitasatoensis. It is active against B. subtilis, S. aureus, M. luteus, and E. coli with MIC values of 0.16, 0.16, 0.08 and >10 μg/mL, respectively. It binds to ribosomes with an IC50 value of 1.2 μM in a radioligand binding assay.
Applications: COVID-19-immunoregulation
Formula: C41H69NO14
References: [1]Tanaka, et al. Quantitative structure-activity relationships of O-acyl derivatives of leucomycin for antimicrobial and ribosome-binding activities. Chem. Pharm. Bull. (Tokyo) 33(7), 2803-2808 (1985).
CAS Number: 78897-52-6
Molecular Weight: 799.98
Research Area: Infection
Target: Others