Licarin A, CAS 51020-86-1

Product Description: Licarin A ((+)-Licarin A), a neolignan, significantly and dose-dependently reduces TNF-α production (IC50=12.6 μM) in dinitrophenyl-human serum albumin (DNP-HSA)-stimulated RBL-2H3 cells. Anti-allergic effects. Licarin A reduces TNF-α and PGD2 production, and COX-2 expression[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C20H22O4

References: [1]Takuya Matsui, et al. Licarin A Is a Candidate Compound for the Treatment of Immediate Hypersensitivity via Inhibition of Rat Mast Cell Line RBL-2H3 Cells. J Pharm Pharmacol. 2015 Dec;67(12):1723-32.

CAS Number: 51020-86-1

Molecular Weight: 326.39

Compound Purity: 98.48

Research Area: Metabolic Disease; Inflammation/Immunology; Neurological Disease

Solubility: DMSO : ≥ 50 mg/mL/H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)

Target: COX;Prostaglandin Receptor;TNF Receptor

• Artikelnummer: MEXHY-N2252-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N2252-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK