Product Description: Loganic acid 6′-O-β-D-glucoside, a iridoidal glucoside, is isolated from the whole plant of Gentiana rhodantha (Gentianaceae). Loganic acid 6′-O-β-D-glucoside inhibits LPS-induced NO and TNF-α production in macrophage RAW264.7 cells[1].
Applications: COVID-19-immunoregulation
Formula: C22H34O15
References: [1]Xu M, et, al. Iridoidal glucosides from Gentiana rhodantha. J Asian Nat Prod Res. May-Jun 2008;10(5-6):491-8./[2]Lv T, et, al. The chemical constituents from the roots of Gentiana crassicaulis and their inhibitory effects on inflammatory mediators NO and TNF-α. Natural Products and Bioprospecting. 2012 Sep 18. (2): 217-221.
CAS Number: 176226-39-4
Molecular Weight: 538.50
Research Area: Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: TNF Receptor