Product Description: Macarangin can be isolated from propolis. Macarangin has DPPH radical-scavenging activity and shows anti-inflammatory activities via inhibiting the activation process of NLRP3 inflammasome[1][2].
Applications: COVID-19-immunoregulation
Formula: C25H26O6
References: [1]Petrova A, et al. New biologically active compounds from Kenyan propolis. Fitoterapia. 2010;81(6):509-514. /[2]Hu Y, et al. Total synthesis/semi-synthesis of natural isopentenyl flavonoids with inhibitory activity on NLRP3 inflammasome. Bioorg Med Chem Lett. 2024;107:129777.
CAS Number: 129385-65-5
Molecular Weight: 422.47
Research Area: Inflammation/Immunology
Target: NOD-like Receptor (NLR);Reactive Oxygen Species