Product Description: Malabaricone B, a naturally occurring plant phenolic, is an orally active α-glucosidase inhibitor with an IC50 of 63.7 µM. Malabaricone B has anticancer, antimicrobial, anti-oxidation and antidiabetic activities[1][2][3].
Applications: Metabolism-sugar/lipid metabolism
Formula: C21H26O4
References: [1]Mrityunjay Tyagi, et al. Spice-derived phenolic, malabaricone B induces mitochondrial damage in lung cancer cells via a p53-independent pathway. Food Funct. 2018 Nov 14;9(11):5715-5727./[2]K Y Orabi, et al. Isolation and characterization of two antimicrobial agents from mace (Myristica fragrans). J Nat Prod. May-Jun 1991;54(3):856-9. /[3]B Prabha, et al. Antidiabetic potential of phytochemicals isolated from the stem bark of Myristica fatua Houtt. var. magnifica (Bedd.) Sinclair. Bioorg Med Chem. 2018 Jul 23;26(12):3461-3467.
CAS Number: 63335-24-0
Molecular Weight: 342.43
Compound Purity: 99.58
Research Area: Cancer; Infection; Metabolic Disease
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Apoptosis;Glucosidase