Product Description: Manumycin B is an antibiobic, and exhibits antitumor activity. Manumycin B is an inhibitor for acetylcholinesterase (AChE) with an IC50 of 15 mM[1][2].
Applications: COVID-19-immunoregulation
Formula: C28H34N2O7
References: [1]Zheng ZH, et al., Isolation and characterization of N98-1272 A, B and C, selective acetylcholinesterase inhibitors from metabolites of an actinomycete strain. J Enzyme Inhib Med Chem. 2007 Feb;22(1):43-9./[2]Grové J J C, et al., The first total synthesis of a type II manumycin antibiotic,(+)-TMC-1 A: the total syntheses of (–)-LL-C10037β and (+)-manumycin B[J]. Chemical Communications, 1999 (5): 421-422.
CAS Number: 139023-58-8
Molecular Weight: 510.58
Research Area: Cancer; Infection
Target: Antibiotic;Cholinesterase (ChE)