Monomethyl lithospermate, CAS 933054-33-2

Product Description: Monomethyl lithospermate activates the PI3K/AKT pathway, which plays a protective role in nerve injury. Monomethyl lithospermate can improve the survival ability of SHSY-5Y cells, inhibit the breakdown of mitochondrial membrane potential (MMOP) and inhibit cell apoptosis. Monomethyl lithospermate also reduced the level of oxidative stress in the brain tissue of rats with middle artery occlusion (MCAO) and improved nerve damage in rats with ischemic stroke (IS)[1].

Formula: C28H24O12

References: [1]Yang F, et al. Monomethyl lithospermate alleviates ischemic stroke injury in middle cerebral artery occlusion mice in vivo and protects oxygen glucose deprivation/reoxygenation induced SHSY-5Y cells in vitro via activation of PI3K/Akt signaling. Front Pharmacol. 2022 Oct 13;13:1024439.

CAS Number: 933054-33-2

Molecular Weight: 552.48

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Akt

• Artikelnummer: MEXHY-N8931-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N8931-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK