Product Description: Murrayafoline A is a carbazole alkaloid that can be extracted from Murraya tetramera. Murrayafoline A directly targets Specificity protein 1 (Sp1), thereby inhibiting NF-κB and MAPK signaling pathways. Murrayafoline A has anti-neuroinflammatory activity[1].
Applications: COVID-19-immunoregulation
Formula: C14H13NO
References: [1]Li CH,et al. Natural carbazole alkaloid murrayafoline A displays potent anti-neuroinflammatory effect by directly targeting transcription factor Sp1 in LPS-induced microglial cells. Bioorg Chem. 2022 Dec;129:106178.
CAS Number: 4532-33-6
Molecular Weight: 211.26
Compound Purity: 97.0
Research Area: Inflammation/Immunology; Neurological Disease