N-Methylcytisine, CAS 486-86-2

Product Description: N-Methylcytisine (Caulophylline), a tricyclic quinolizidine alkaloid, exerts hypoglycaemic, analgesic and anti-inflammatory activities. N-methylcytisine is a selective ligand of nicotinic receptors of acetylcholine in the central nervous system and has a high affinity (Kd = 50 nM) to nicotinic acetylcholine receptors (nAChR) from squid optical ganglia[1][2].

Applications: COVID-19-immunoregulation

Formula: C12H16N2O

References: [1]Jiao YF, et al. N-Methylcytisine Ameliorates Dextran-Sulfate-Sodium-Induced Colitis in Mice by Inhibiting the Inflammatory Response. Molecules. 2018 Feb 25;23(3). pii: E510./[2]Pliashkevich IuG, et al. [N-methylcytisine--a selective ligand of nicotinic receptors of acetylcholine in the CNS]. Biull Eksp Biol Med. 1987 Dec;104(12):690-2.

CAS Number: 486-86-2

Molecular Weight: 204.27

Compound Purity: 99.81

Research Area: Inflammation/Immunology

Solubility: DMSO : 120 mg/mL (ultrasonic)/H2O : 100 mg/mL (ultrasonic)

Target: nAChR

• Artikelnummer: MEXHY-N0443-50
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N0443-50
• Green Labware: Nein
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK