N6-Benzyladenosine, CAS 4294-16-0

Product Description: N6-Benzyladenosine is an adenosine receptor agonist, has a cytoactive activity. N6-Benzyladenosine arrests cell cycle at G0/G1 phase and induces cell apoptosis. N6-Benzyladenosine also exerts inhibitory effect on T. gondii adenosine kinase and glioma[1]-[5].

Applications: COVID-19-immunoregulation

Formula: C17H19N5O4

References: [1]Kaminek M, et al. Cytokinin activities of N6-benzyladenosine derivatives hydroxylated on the side-chain phenyl ring. Journal of Plant Growth Regulation. 1987. 6(2):113./[2]Castiglioni S, et al. N6-isopentenyladenosine and its analogue N6-benzyladenosine induce cell cycle arrest and apoptosis in bladder carcinoma T24 cells. Anticancer Agents Med Chem. 2013 May;13(4):672-8. /[3]Mlejnek P. Caspase inhibition and N6-benzyladenosine-induced apoptosis in HL-60 cells. J Cell Biochem. 2001;83(4):678-89./[4]Kim YA, et al. Synthesis, biological evaluation and molecular modeling studies of N6-benzyladenosine analogues as potential anti-toxoplasma agents. Biochem Pharmacol. 2007 May 15;73(10):1558-72. /[5]Grimaldi M, et al. NMR for screening and a biochemical assay: Identification of new FPPS inhibitors exerting anticancer activity. Bioorg Chem. 2020 May;98:103449.

CAS Number: 4294-16-0

Molecular Weight: 357.36

Compound Purity: 99.67

Research Area: Cancer; Inflammation/Immunology

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: Adenosine Receptor;Apoptosis

• Artikelnummer: MEXHY-N7844-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N7844-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK