Product Description: Naphthazarin (DHNQ) is a naturally occurring compound. Naphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, interference with lysosomal function and p53-dependent p21 activation. Naphthazarin triggers apoptosis and has anti-tumor effects[1][2].
Applications: Cancer-programmed cell death
Formula: C10H6O4
References: [1]Seon Young Choi, et al. Naphthazarin has a protective effect on the 1-methyl-4-phenyl-1,2,3,4-tetrahydropyridine-induced Parkinson's disease model. J Neurosci Res. 2012 Sep;90(9):1842-9./[2]Omar Aljanadi, et al. Stimulation of Suicidal Erythrocyte Death by Naphthazarin. Basic Clin Pharmacol Toxicol. 2015 Dec;117(6):369-74.
CAS Number: 475-38-7
Molecular Weight: 190.15
Compound Purity: 99.15
Research Area: Cancer; Neurological Disease
Solubility: DMSO : 7.14 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Apoptosis