Nyasol, CAS 96895-25-9

Product Description: Nyasol ((-)-Nyasol) is an active compound that has antifungal, antibacterial, antileishmanial, hyaluronidase inhibition activities. Nyasol inhibits LTB4 binding to human neutrophils. Nyasol suppresses neuroinflammatory response through the inhibition of I-κB degradation in LPS (HY-D1056)-stimulated BV-2 microglial cells[1][2].

Applications: COVID-19-immunoregulation

Formula: C17H16O2

References: [1]Lim H, et al. (-)-Nyasol (cis-hinokiresinol), a norneolignan from the rhizomes of Anemarrhena asphodeloides, is a broad spectrum inhibitor of eicosanoid and nitric oxide production. Arch Pharm Res. 2009 Nov;32(11):1509-14./[2]Iida Y, et al. In vitro synergism between nyasol, an active compound isolated from Anemarrhena asphodeloides, and azole agents against Candida albicans. Planta Med. 2000 Jun;66(5):435-8./[3]Lee HJ, et al. (-)-Nyasol, isolated from Anemarrhena asphodeloides suppresses neuroinflammatory response through the inhibition of I-κBα degradation in LPS-stimulated BV-2 microglial cells. J Enzyme Inhib Med Chem. 2013 Oct;28(5):954-9.

CAS Number: 96895-25-9

Molecular Weight: 252.31

Research Area: Infection; Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Bacterial;Fungal;Leukotriene Receptor;NO Synthase;Parasite

• Artikelnummer: MEXHY-138050-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-138050-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK