Ouabain (Octahydrate), CAS 11018-89-6

Product Description: Ouabain Octahydrate is an inhibitor of Na+/K+-ATPase, used for the treatment of congestive heart failure.

Applications: COVID-19-immunoregulation

Formula: C29H60O20

References: [1]Kobayashi M, et al. The cardiac glycoside ouabain activates NLRP3 inflammasomes and promotes cardiac inflammation and dysfunction. PLoS One. 2017 May 11;12(5):e0176676./[2]Venugopal J, et al. Ouabain promotes partial epithelial to mesenchymal transition (EMT) changes in human autosomal dominant polycystic kidney disease (ADPKD) cells. Exp Cell Res. 2017 Jun 15;355(2):142-152./[3]Lima DB, et al. Ouabain-induced alterations in ABCB1 of mesenteric lymph nodes and thymocytes of rats and mice. Oncol Lett. 2016 Dec;12(6):5275-5280./[4]Meng L, et al. Ouabain induces apoptosis and autophagy in Burkitt's lymphoma Raji cells. Biomed Pharmacother. 2016 Dec;84:1841-1848.

CAS Number: 11018-89-6

Molecular Weight: 728.77

Compound Purity: 99.96

Research Area: Cardiovascular Disease; Cancer

Solubility: DMSO : ≥ 125 mg/mL/H2O : 10 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Autophagy;Na+/K+ ATPase

• Artikelnummer: MEXHY-B0542-500
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0542-500
• Verpackungseinheit: 500 mg
• Mengeneinheit: STK