Product Description: Pheanthine (Compound 2) is an antiplasmodial agent, that inhibits chloroquine-resistant Plasmodium falciparum K-1 (IC50 is 0.8 μM) and chloroquine-sensitive P. falciparum strain NF54 A19A (IC50 of 0.03 μM). Pheanthine exhibits low cytotoxicity in human lung fibrosblast (MRC-5, IC50 is 11.2 μM) and macrophages (PMM, IC50 is 8 μM)[1].
Formula: C38H42N2O6
References: [1]Cimanga Kanyanga R., et al.,Isolation and structure elucidation of two antiprotozoal bisbenzylisoquinoline alkaloids from Triclisia gilletii stem bark. Phytochemistry Letters. 2018.
CAS Number: 1263-79-2
Molecular Weight: 622.75
Research Area: Infection
Solubility: 10 mM in DMSO
Target: Parasite