Phloracetophenone, CAS 480-66-0

Product Description: Phloracetophenone (2,4,6-trihydroxyacetophenone) is the aglycone part of acetophenone glycoside obtained from Curcuma comosa Roxb, with cholesterol-lowering activity. Phloracetophenone enhances cholesterol 7α-hydroxylase (CYP7A1) activity[1]. Phloracetophenone stimulats bile secretion mediated through Mrp2[2].

Applications: Metabolism-sugar/lipid metabolism

Formula: C8H8O4

References: [1]Charoenteeraboon J, et al. Induction of human cholesterol 7alpha-hydroxylase in HepG2 cells by 2,4,6-trihydroxyacetophenone. Eur J Pharmacol. 2005 May 16;515(1-3):43-6./[2]Piyachaturawat P, et al. Choleretic activity of phloracetophenone in rats: structure-function studies using acetophenone analogues. Eur J Pharmacol. 2000 Jan 10;387(2):221-7.

CAS Number: 480-66-0

Molecular Weight: 168.15

Compound Purity: 99.98

Research Area: Infection; Metabolic Disease

Solubility: DMSO : 25 mg/mL (ultrasonic)/H2O : 2 mg/mL (ultrasonic)

Target: Antibiotic;Bacterial;Cytochrome P450

• Artikelnummer: MEXHY-W008226-1G
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W008226-1G
• Green Labware: Nein
• Verpackungseinheit: 1 g
• Mengeneinheit: STK