Product Description: Phomoxanthone A is a xanthone dimer, which can be isolated from Phomopsis. Phomoxanthone A exhibits antimalarial and antitubercular activities against Plasmodium falciparum (K1, multidrug-resistant strain, IC50 is 0.11 µg/mL) and Mycobacterium tuberculosis (H37Ra strain, MIC is 0.50 µg/mL). Phomoxanthone A exhibits cytotoxicity in cells KB, BC-1 and Vero, IC50 is 0.99, 0.51 and 1.4 µg/mL, respectively[1].
Applications: COVID-19-immunoregulation
Formula: C38H38O16
References: [1]Isaka M, et al., Phomoxanthones A and B, novel xanthone dimers from the endophytic fungus Phomopsis species. J Nat Prod. 2001 Aug;64(8):1015-8.
CAS Number: 359844-69-2
Molecular Weight: 750.70
Research Area: Cancer; Infection
Target: Parasite