Physalin B, CAS 23133-56-4

Product Description: Physalin B, one of the major active steroidal constituents of Cape gooseberry, induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway. Physalin B inhibits the ubiquitin-proteasome pathway and induces incomplete autophagic response in human colon cancer cells in vitro[1][2].

Applications: Cancer-programmed cell death

Formula: C28H30O9

References: [1]Wang A, et al. Physalin B induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway. Biomed Pharmacother. 2018;101:334-341./[2]Ma YM, et al. Physalin B not only inhibits the ubiquitin-proteasome pathway but also induces incomplete autophagic response in human colon cancer cells in vitro. Acta Pharmacol Sin. 2015;36(4):517-527.

CAS Number: 23133-56-4

Molecular Weight: 510.53

Compound Purity: 96.90

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Apoptosis;Autophagy

• Artikelnummer: MEXHY-N7695-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N7695-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK