Quinine (hemisulfate), CAS 804-63-7

Product Description: Quinine hemisulfate is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine hemisulfate is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100?mV with an IC50 of 169 μM[1][2].

Applications: COVID-19-anti-virus

Formula: C20H24N2O2.1/2H2SO4

References: [1]Shilu Malakar，et al. Drug repurposing of quinine as antiviral against dengue virus infection. Virus Res. 2018 Aug 15;255:171-178. doi: 10.1016/j.virusres.2018.07.018. Epub 2018 Jul 25./[2]Ebenezer O Farombi, et al. Quercetin protects against testicular toxicity induced by chronic administration of therapeutic dose of quinine sulfate in rats. J Basic Clin Physiol Pharmacol. 2012 Feb 27;23(1):39-44./[3]Jhanwar, Deepika，et al. Chemoprevention of DMBA induced skin carcinogenesis in swiss albino mice by quinine sulfate.(2016): 2636-2640.

CAS Number: 804-63-7

Molecular Weight: 373.45

Compound Purity: 99.0

Research Area: Infection

Solubility: 10 mM in DMSO

Target: Dengue virus;Flavivirus;Parasite;Potassium Channel

• Artikelnummer: MEXHY-B0433B-500
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0433B-500
• Verpackungseinheit: 500 mg
• Mengeneinheit: STK