Product Description: Ramentaceone (7-Methyljuglon), a naphthoquinone that can be isolated from Drosera sp., inhibits PI3K activity. Ramentaceone (7-Methyljuglon) reduces the expression of the PI3K protein and inhibits the phosphorylation of the Akt protein in breast cancer cells. Ramentaceone (7-Methyljuglon) induces apoptosis[1].
Formula: C11H8O3
References: [1]Anna Kawiak, et al. Ramentaceone, a Naphthoquinone Derived from Drosera sp., Induces Apoptosis by Suppressing PI3K/Akt Signaling in Breast Cancer Cells. PLoS One. 2016 Feb 3;11(2):e0147718.
CAS Number: 14787-38-3
Molecular Weight: 188.18
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Apoptosis;PI3K