Rapanone, CAS 573-40-0

Product Description: Rapanone is a natural benzoquinone. Rapanone exhibits a broad spectrum of biological actions, including anti-tumor, antioxidant, anti-inflammatory, antibacterial and antiparasitic. Rapanone also is a potent and selective human synovial PLA2 inhibitor, with an IC50 of 2.6 μM[1][2][3][4].

Applications: COVID-19-immunoregulation

Formula: C19H30O4

References: [1]Andreu GLP, et, al. Rapanone, a naturally occurring benzoquinone, inhibits mitochondrial respiration and induces HepG2 cell death. Toxicol In Vitro. 2020 Mar;63:104737./[2]Morais LS, et, al. Antileishmanial compounds from Connarus suberosus: Metabolomics, isolation and mechanism of action. PLoS One. 2020 Nov 6;15(11):e0241855./[3]Vega-Hernández K, et, al. Discerning the antioxidant mechanism of rapanone: A naturally occurring benzoquinone with iron complexing and radical scavenging activities. J Inorg Biochem. 2017 May;170:134-147./[4]Ospina LF, et, al. Inhibition of acute and chronic inflammatory responses by the hydroxybenzoquinonic derivative rapanone. Planta Med. 2001 Dec;67(9):791-5.

CAS Number: 573-40-0

Molecular Weight: 322.44

Compound Purity: 99.20

Research Area: Cancer; Infection; Inflammation/Immunology

Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Apoptosis;Bacterial;Parasite;Phospholipase

• Artikelnummer: MEXHY-N8213-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N8213-10.1
• Green Labware: Nein
• Verpackungseinheit: 10mM/1mL
• Mengeneinheit: STK