Product Description: Rogersonin E can be isolated from an Ophiocordyceps-associated fungus, Clonostachys rogersoniana. Rogersonin E downregulates the expression of PD-L1 protein in MDA-MB-231 and A549 cells[1].
Formula: C24H29N5O9
References: [1]Hou X, et al. Rogersonins C-F, 9H-Imidazo[2,1-i]purine-Incorporating Adenine-Polyketide Hybrids from an Ophiocordyceps-Associated Clonostachys rogersoniana. J Nat Prod. 2024 Jun 28;87(6):1618-1627.
Molecular Weight: 531.52
Research Area: Cancer
Target: PD-1/PD-L1