Rubitecan, CAS 91421-42-0

Product Description: Rubitecan (RFS 2000), a Camptothecin derivative, is an orally active topoisomerase I inhibitor with broad antitumor activity, and induces protein-linked DNA single-strand breaks, thereby blocking DNA and RNA synthesis in dividing cells[1][2][3].

Applications: Cancer-programmed cell death

Formula: C20H15N3O6

References: [1]Burris HA 3rd, et al. Phase II trial of oral rubitecan in previously treated pancreatic cancer patients. Oncologist. 2005 Mar;10(3):183-90./[2]Rubitecan: 9-NC, 9-Nitro-20(S)-camptothecin, 9-nitro-camptothecin, 9-nitrocamptothecin, RFS 2000, RFS2000. Drugs R D. 2004;5(5):305-11./[3]Rubitecan/[4]Xia M, et al. Identification of repurposed small molecule drugs for chordoma therapy. Cancer Biol Ther. 2013 Jul;14(7):638-47.

CAS Number: 91421-42-0

Molecular Weight: 393.35

Compound Purity: 99.23

Research Area: Cancer

Solubility: DMSO : 62.5 mg/mL (ultrasonic)

Target: Topoisomerase

• Artikelnummer: MEXHY-13744-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-13744-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK