Product Description: Schisantherin D is a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra sphenanthera. Schisantherin D shows anti-HIV replication activities with an EC50 of 0.5 μg/mL. Schisantherin D inhibits endothelin receptor B (ETBR) and has hepatoprotective effects[1][2].
Applications: COVID-19-anti-virus
Formula: C29H28O9
References: [1]D F Chen, et al. Two new lignans, interiotherins A and B, as anti-HIV principles from Kadsura interior. J Nat Prod. 1996 Nov;59(11):1066-8./[2]Jin-Biao Xu, et al. Lignans from Schisandra chinensis ameliorate alcohol and CCl 4-induced long-term liver injury and reduce hepatocellular degeneration via blocking ETBR. J Ethnopharmacol. 2020 Aug 10;258:112813.
CAS Number: 64917-82-4
Molecular Weight: 520.53
Compound Purity: 99.66
Research Area: Infection
Solubility: 10 mM in DMSO
Target: HIV