Product Description: Sempervirine is an indole alkaloid isolated from Gelsemium sempervirens with anti-tumor activities. Sempervirine is against sempervirine-sensitive tumor cells with EC50 values of 2.7 μM, 1.77 μM, and 1.96 μM for Raji, MDA-MB-231 and HeLa cells, respectively[2].
Applications: Cancer-programmed cell death
Formula: C19H16N2
References: [1]Noriyuki Kogure, et al. Total synthesis and full NMR assignment of ourouparine, a yohimbane-type indole alkaloid isolated from Gelsemium sempervirens. Journal of Natural Medicines volume
CAS Number: 549-92-8
Molecular Weight: 272.34
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Others