Product Description: Sennidin A, isolated from the leaves of Cassia angustifolia, inhibits HCV NS3 helicase, with an IC50 of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation[1][2].
Applications: COVID-19-anti-virus
Formula: C30H18O10
References: [1]Furuta A, et al. Identification of Hydroxyanthraquinones as Novel Inhibitors of Hepatitis C Virus NS3 Helicase. Int J Mol Sci. 2015 Aug 7;16(8):18439-53./[2]Daigo Abe, et al. Sennidin stimulates glucose incorporation in rat adipocytes. Life Sciences. 2006.
CAS Number: 641-12-3
Molecular Weight: 538.46
Research Area: Infection
Solubility: 10 mM in DMSO
Target: Akt;GLUT;HCV